New approaches in prostate cancer treatment

June 22, 2011

The researchers of one British universities have identified two proteins in urine which may serve as a sign of a tumor process beginning in the prostate gland. With the help of new markers it will be possible to detect with the exact accuracy the presence of tumor in the body long before the disease symptoms occur. Furthermore, the new diagnostic method is much more precise than the existing ones and it often allows to avoid unnecessary invasive procedures.

The discovery in diagnostics will allow to successfully treat prostate cancer. Currently it is possible to identify the prostate cancer relatively early with the help of blood test for prostate – specific antigen (PSA). However, this method is exact only in 60% of cases. In addition, it reports about the changes in the prostate gland also in patients with benign tumors.

Usually doctors have to do a prostate biopsy in patients with an increased PSA level, which is an invasive manipulation, a traumatic one and is connected with the risk of infection. In its turn, even the prostate gland biopsy may show a negative result in the case when the needle gets into a still healthy part of the prostate gland.

The new diagnostic method elaborated by the researchers from the Bristol University , is based on the finding of insignificantly small number of two proteins in the urine.

The important moment is that it will be possible to differentiate cancer forms without biopsy at an early stage with the help of a new test – some types of prostate cancer are curable by hormonal and chemotherapy, meanwhile the others are highly aggressive forms, demanding surgical intervention.

«;Proteins, identified by us as markers, may be in urine for many years before there are any clinical symptoms. That is why, the use of this technology for a mass examination of risk groups has a great potential», - supposes Professor Mari-Anne Rowlands, the head of the research group.